A greater proportion of 197+ cells than of other T cells isolated from blood and lymph had G2/M phase DNA content, when incredibly couple of had S phase DNA content. The response of 197+ cells with regards to adjust in relative numbers following in vivo allogeneic challenge was rather unique to that of CD4+ or CD8+ cells. As opposed to increasing to a peak at 5-8 days after challenge and after that declining, the percentage of 197+ cells rose steadily with no evidence of decline by 14 days.
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